I had an EA3532 (5 Channel) amp driving 5.25 and 6.9 Point Source all running off a CD5441 head unit. The sub channel on that amp could really only support a single Kicker Comp sub. I tried running 2 Kicker Comps but the single channel couldn't handle it. To me a single 10 inch kicker comp was just barely adequate at max volume to integrate into the rest of the system (and even then it was only barely adequate for rock music, and not stuff with more significant bass).
When I tried running the two subs, I had the amp mounted on the back of the seat (spare moved a few inches away from original location). I used two sealed "truck" enclosures for the subs, which were more tall and long as opposed to cube shaped, and could tuck them (with a slight angle) in-between the tail lights and wheel wells. The subs were facing each other. Fairly reasonable amount of trunk space remained without having to get custom enclosures built. These boxes were definately less than 1.0 cu in, probabaly close to .75 cu in each.
If you will be running the EA3422, then a pair of JL 10W0, 10 inch Kicker Comps, or similar subs would be the ticket. I think this would work well for your needs without being too little or too much. I don't think there is enough power there to drive a pair of JL W3's or Comp VRs adequately. One thing to keep in mind about the eclipse amps are that they don't measure their power conservatively. The power tends to be right on what they say it is (as opposed to amps that produce a touch more than what they say). You get excellent quality, clean sound out of Eclipse amps, but you don't get massive amounts of power. So, if you want to run a sub off an Eclipse amp, error towards a more powerful amp (or less power-hungry sub).
In the end I decided to sacrifice more trunk space (but still kept the spare) to run a pair of 12 inch Kicker Comp VRs. I also had to get larger enclosures and a significantly larger Eclipse amp to drive them.